The annotation score provides a heuristic measure of the annotation nội dung of a mni-alive.comKB entry or proteome. This score cannot be used as a measure of the accuracy of the annotation as we cannot define the "correct annotation" for any given protein.More...
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-Protein inferred from homologyiThis indicates the type of evidence that supports the existence of the protein. lưu ý that the "protein existence" evidence does not give information on the accuracy or correctness of the sequence(s) displayed.More...
Select a section on the left lớn see content.
This section provides any useful information about the protein, mostly biological knowledge.More...
FunctioniCautionThe sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Information which has been imported from another database using automatic procedures.
More...
Automatic assertion inferred from database entriesiThis subsection of the Function section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.More...
Catalytic activityi2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2OUniRule annotation
Information which has been generated by the mni-alive.comKB automatic annotation system, without manual validation.
More...
Automatic assertion according khổng lồ rulesiEC:4.2.1.9UniRule annotation
Automatic assertion according to lớn rulesi
Source: Rhea. Show »« Hide
2,3-dihydroxy-3-methylbutanoate
=
3-methyl-2-oxobutanoate
+
H2O
This subsection of the "Function" section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.More...
Cofactori<4Fe-4S> clusterUniRule annotation
Automatic assertion according khổng lồ rulesi
Note: Binds 1 <4Fe-4S> cluster.UniRule annotationAutomatic assertion according to rulesi
This subsection of the "Function" section describes the metabolic pathway(s) associated with a protein.More...
Pathwayi: L-isoleucine biosynthesisThis protein is involved in step 3 of the subpathway that synthesizes L-isoleucine from 2-oxobutanoate.UniRule annotationAutomatic assertion according to lớn rulesi
Proteins known khổng lồ be involved in the 4 steps of the subpathway in this organism are: This subpathway is part of the pathway L-isoleucine biosynthesis, which is itself part of Amino-acid biosynthesis.View all proteins of this organism that are known khổng lồ be involved in the subpathway that synthesizes L-isoleucine from 2-oxobutanoate, the pathway L-isoleucine biosynthesis và in Amino-acid biosynthesis.Pathwayi: L-valine biosynthesisThis protein is involved in step 3 of the subpathway that synthesizes L-valine from pyruvate.UniRule annotation
Automatic assertion according lớn rulesi
Proteins known khổng lồ be involved in the 4 steps of the subpathway in this organism are: This subpathway is part of the pathway L-valine biosynthesis, which is itself part of Amino-acid biosynthesis.View all proteins of this organism that are known lớn be involved in the subpathway that synthesizes L-valine from pyruvate, the pathway L-valine biosynthesis & in Amino-acid biosynthesis.Sites
| This subsection of the Function section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the "Description" field.More... Metal bindingi | 123 | Iron-sulfur (4Fe-4S)UniRule annotation Automatic assertion according khổng lồ rulesi | 1 | |
| Metal bindingi | 195 | Iron-sulfur (4Fe-4S)UniRule annotation Automatic assertion according to lớn rulesi | 1 |
The Gene Ontology (GO) project provides a set of hierarchical controlled vocabulary split inkhổng lồ 3 categories:More...
GO - Molecular functioniComplete GO annotation on QuickGO ...
GO - Biological processi
Complete GO annotation on QuickGO ...
mni-alive.comKB Keywords constitute a controlled vocabulary with a hierarchical structure. Keywords summarise the content of a mni-alive.comKB entry và facilitate the search for proteins of interest.More...
Keywordsi| Molecular function | LyaseUniRule annotation Automatic assertion according khổng lồ rulesi ImportedAutomatic assertion inferred from database entriesi ARBA annotationAutomatic assertion according lớn rulesi |
| Biological process | Amino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation Automatic assertion according to lớn rulesi ARBA annotationAutomatic assertion according to rulesi |
| Ligand | 4Fe-4SUniRule annotation Automatic assertion according lớn rulesi ARBA annotationAutomatic assertion according lớn rulesi , Iron, Iron-sulfur, Metal-binding |
UniPathway: a resource for the exploration và annotation of metabolic pathways More...UniPathwayi | UPA00047;UER00057UPA00049;UER00061 |
This section provides information about the protein và gen name(s) & synonym(s) & about the organism that is the source of the protein sequence.More...
Names và Taxonomyi| This subsection of the Names và taxonomy section provides an exhaustive sầu các mục of all names of the protein, from commonly used lớn obsolete, khổng lồ allow unambiguous identification of a protein.More... Protein namesi | Recommended name: Dihydroxy-acid dehydrataseUniRule annotation Automatic assertion according khổng lồ rulesi (EC:4.2.1.9UniRule annotationAutomatic assertion according to rulesi )Short name: DADUniRule annotation Automatic assertion according khổng lồ rulesi |
| This subsection of the Names và taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: "Name", "Synonyms", "Ordered locus names" and "ORF names".More... Gene namesi | Name:ilvImported Automatic assertion inferred from database entriesi Synonyms:ilvDUniRule annotation Automatic assertion according to lớn rulesi ORF Names:AFERRI_370019Imported Automatic assertion inferred from database entriesi |
| This subsection of the Names & taxonomy section provides information on the name(s) of the organism that is the source of the protein sequence.More... Organismi | Acidithiobacillus ferrivoransImported Automatic assertion inferred from database entriesi |
| This subsection of the Names & taxonomy section shows the unique identifier assigned by the NCBI khổng lồ the source organism of the protein. This is known as the "taxonomic identifier" or "taxid".More... Xem thêm: Ngon Tê Lưỡi Với 3 Cách Xào Mắm Ruốc Ăn Trái Cây, Cách Làm Mắm Ruốc Chấm Xoài Ngon Nhất Cho Ngày Hè Taxonomic identifieri | 160808 |
| This subsection of the Names & taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.More... Taxonomic lineagei | cellular organisms › Bacteria › Proteobacteria › Acidithiobacillia › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus |
| This subsection of the Names và taxonomy section is present for entries that are part of a proteome, i.e. of a phối of proteins thought khổng lồ be expressed by organisms whose genomes have been completely sequenced.More... Proteomesi |
This section provides information on sequence similarities with other proteins & the domain(s) present in a protein.More...
Family và DomainsiCoiled coil| This subsection of the "Family & domains" section denotes the positions of regions of coiled coil within the protein.More... Coiled coili | 226 – 246 | Sequence analysis Automatic assertion according to sequence analysisi Add BLAST | 21 |
This subsection of the "Family & domains" section provides information about the sequence similarity with other proteins.More...
Sequence similaritiesiBelongs khổng lồ the IlvD/Edd family.UniRule annotation
Automatic assertion according lớn rulesi
ARBA annotationAutomatic assertion according to lớn rulesi
Keywords - DomainiCoiled coilSequence analysis
Automatic assertion according khổng lồ sequence analysisi
Family & domain name databasesGene3D Structural and Functional Annotation of Protein Families More...Gene3Di | 3.50.30.80, 1 hit |
HAMAP database of protein families More...HAMAPi | MF_00012, IlvD, 1 hit |
Integrated resource of protein families, domains and functional sites More...InterProi | View protein in InterProIPR042096, Dihydro-acid_dehy_CIPR004404, DihydroxyA_deHydtaseIPR000581, DiOHA_6PGluconate_deHydtaseIPR020558, DiOHA_6PGluconate_deHydtase_CSIPR037237, IlvD/EDD_N |
Pfam protein domain database More...Pfami | View protein in PfamPF00920, ILVD_EDD, 1 hit |
Superfamily database of structural and functional annotation More...SUPFAMi | SSF143975, SSF143975, 1 hit |
TIGRFAMs; a protein family database More...TIGRFAMsi | TIGR00110, ilvD, 1 hit |
PROSITE; a protein domain & family database More...PROSITEi | View protein in PROSITEPS00886, ILVD_EDD_1, 1 hitPS00887, ILVD_EDD_2, 1 hit |
This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent lớn the sequence(s), including length and molecular weight. The information is filed in different subsections. The current subsections và their nội dung are listed below:More...
SequenceiThis subsection of the Sequence section indicates if the canonical sequence displayed by default in the entry is complete or not.More...
Sequence statusi: Complete.A0A060UN89-1
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10 20 30 40 50MSDNRRSKTV TQGVQRSPNR ALLRAVGFGD QDFDKPIVGV ANAHSSITPC 60 70 80 90 100NIGIGALATR AEAALKAAGA MPQTFGTITI SDGISMGTAG MKYSLVSREV 110 1trăng tròn 130 140 150IADSIETVCQ GQSMDGVLAL GGCDKNMPGA MIAIARMNIP AIFVYGGTIK 160 170 180 190 200PGHYRGQDLT IMSAFEAVGQ HTVHKIDDEE LLEIERRACP. GAGSCGGMYT 210 220 230 240 250ANTMSSIFEA MGMSLPYSST MAAEDAEKAE SAAQSAEVLV SAIQKQILquảng cáo 260 270 280 290 300QILTRQAFEN AIAVAMAVGG STNAVLHLLA IAHAAQVPLT LDDFEAMRGR 310 3trăng tròn 330 340 350VPVLCDLKPS GRFVATDLHR AGGIPQVMKI LLAHGVLHGD ALTISGQTLA 360 370 380 390 400EVLQDVPSEA RTDQEVIRPW NHPIYAQGHL AILKGNLAPE GAVAKITGFI 410 4đôi mươi 430 440 450THKITGPARV FESEESCMKA ILAQKIKPGD VVVIRYEGPK GGPGMREMLS 460 470 480 490 500PTSAIIGEGL GDSVGLITDG RFSGATYGMV VGHVAPEAAV GGTIALVIEG 510 5đôi mươi 530 540 550DSVTIDPEQR LLQLNVSDEE IERRRAVWQA PAPRHTRGVL AKYAKLVSSA SKGAVTD
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Length:557
Mass (Da):58,557
Last modified:September 3, 2014 - v1
The checksum is a size of redundancy kiểm tra that is calculated
from the sequence. It is useful for tracking sequence updates.
It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.
However mni-alive.comKB may contain entries with identical sequences in case of multiple genes (paralogs).
The checksum is computed as the sequence 64-bit Cyclic Redundancy Chechồng value (CRC64) using the generator polynomial: x64 + x4 + x3 + x + 1. The algorithm is described in the ISO 3309 standard.
Press W.H., Flannery B.P., Teukolsky S.A. và Vetterling W.T. Cyclic redundancy và other checksums Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993))
Checksum:iB4E6F6A0E442B3ADBLASTProtParamProtScaleCompute pI/MWPeptideMassPeptideCutterGO
Sequence databases
| Select the link destinations: EMBL nucleotide sequence database More...EMBLiGenBank nucleotide sequence database More...GenBankiDNA Data Bank of Japan; a nucleotide sequence database More...DDBJiLinks Updated | CCCS020000031 Genomic DNA Translation: CDQ09915.1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NCBI Reference Sequences This section provides link to lớn proteins that are similar khổng lồ the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in mni-alive.com Reference Clusters (UniRef).More... Similar proteinsi
Full view
Full view This section is used to point to lớn information related to entries and found in data collections other than mni-alive.comKB.More... Cross-referencesiSequence databases
This section provides general information on the entry.More... Entry informationi
Toolsbộ vi xử lý Core dataSupporting dataInformation CÙNG CHUYÊN MỤC |
